Results
| May 8, 2021 |
| Salford City | 3 - 0 | Leyton Orient |
| Morecambe | 2 - 0 | Bradford City |
| Cambridge United | 3 - 0 | Grimsby Town |
| Carlisle United | 0 - 0 | Walsall |
| Cheltenham Town | 4 - 1 | Harrogate Town |
| Crawley Town | 1 - 4 | Bolton Wanderers |
| Exeter City | 1 - 1 | Barrow |
| Oldham Athletic | 0 - 3 | Forest Green R… |
| Port Vale | 0 - 3 | Mansfield Town |
| Scunthorpe United | 0 - 1 | Stevenage |
| Southend United | 1 - 1 | Newport County |
| Tranmere Rovers | 0 - 0 | Colchester United |
Table
| Team | MP | W | D | L | F | A | G | P |
|---|
| Cheltenham Town | 46 | 24 | 10 | 12 | 61 | 39 | +22 | 82 |
| Cambridge United | 46 | 24 | 8 | 14 | 73 | 49 | +24 | 80 |
| Bolton Wanderers | 46 | 23 | 10 | 13 | 59 | 50 | +9 | 79 |
| Morecambe | 46 | 23 | 9 | 14 | 69 | 58 | +11 | 78 |
| Newport County | 46 | 20 | 13 | 13 | 57 | 42 | +15 | 73 |
| Forest Green R… | 46 | 20 | 13 | 13 | 59 | 51 | +8 | 73 |
| Tranmere Rovers | 46 | 20 | 13 | 13 | 55 | 50 | +5 | 73 |
| Salford City | 46 | 19 | 14 | 13 | 54 | 34 | +20 | 71 |
| Exeter City | 46 | 18 | 16 | 12 | 71 | 50 | +21 | 70 |
| Carlisle United | 46 | 18 | 12 | 16 | 60 | 51 | +9 | 66 |
| Leyton Orient | 46 | 17 | 10 | 19 | 53 | 55 | -2 | 61 |
| Crawley Town | 46 | 16 | 13 | 17 | 56 | 62 | -6 | 61 |
| Port Vale | 46 | 17 | 9 | 20 | 57 | 57 | +0 | 60 |
| Stevenage | 46 | 14 | 18 | 14 | 41 | 41 | +0 | 60 |
| Bradford City | 46 | 16 | 11 | 19 | 48 | 53 | -5 | 59 |
| Mansfield Town | 46 | 13 | 19 | 14 | 57 | 55 | +2 | 58 |
| Harrogate Town | 46 | 16 | 9 | 21 | 52 | 61 | -9 | 57 |
| Oldham Athletic | 46 | 15 | 9 | 22 | 72 | 81 | -9 | 54 |
| Walsall | 46 | 11 | 20 | 15 | 45 | 53 | -8 | 53 |
| Colchester United | 46 | 11 | 18 | 17 | 44 | 61 | -17 | 51 |
| Barrow | 46 | 13 | 11 | 22 | 53 | 59 | -6 | 50 |
| Scunthorpe United | 46 | 13 | 9 | 24 | 41 | 64 | -23 | 48 |
| Southend United | 46 | 10 | 15 | 21 | 29 | 58 | -29 | 45 |
| Grimsby Town | 46 | 10 | 13 | 23 | 37 | 69 | -32 | 43 |
Upcoming matches
| May 18, 2021 |
| Newport County | 19:15 | Forest Green R… |
| May 20, 2021 |
| Tranmere Rovers | 17:00 | Morecambe |
| May 23, 2021 |
| Morecambe | 11:30 | Tranmere Rovers |
| Forest Green R… | 17:30 | Newport County |
